| 17p deletion |
Copy Number (arm level) |
2 |
3 |
| 5q deletion |
Copy Number (arm level) |
2 |
2 |
| ABL1 p.T315I |
Somatic Variant |
4 |
5 |
| AKT1 amplification |
Copy Number |
3 |
4 |
| AKT1 somatic variants |
Somatic Variant |
3 |
4 |
| ATM oncogenic variants |
Somatic Variant |
2 |
2 |
| ATM pathogenic variants |
Germline Variant |
2 |
2 |
| ATR oncogenic variants |
Somatic Variant |
1 |
1 |
| ATR pathogenic variants |
Germline Variant |
1 |
1 |
| BARD1 oncogenic variants |
Somatic Variant |
2 |
2 |
| BARD1 pathogenic variants |
Germline Variant |
1 |
1 |
| BCR::ABL1 |
Rearrangement |
14 |
29 |
| BCR::ABL1 |
Rearrangement |
11 |
23 |
| BRAF p.V600E |
Somatic Variant |
18 |
42 |
| BRAF p.V600K |
Somatic Variant |
10 |
22 |
| BRAF rearrangements |
Rearrangement |
1 |
1 |
| BRCA1 oncogenic variants |
Somatic Variant |
15 |
25 |
| BRCA1 pathogenic variants |
Germline Variant |
21 |
36 |
| BRCA2 oncogenic variants |
Somatic Variant |
15 |
25 |
| BRCA2 pathogenic variants |
Germline Variant |
21 |
36 |
| BRIP1 oncogenic variants |
Somatic Variant |
2 |
2 |
| BRIP1 pathogenic variants |
Germline Variant |
2 |
2 |
| CD117 + |
Protein expression |
1 |
3 |
| CD19 + |
Protein expression |
2 |
8 |
| CD20 + |
Protein expression |
14 |
15 |
| CD22 + |
Protein expression |
2 |
3 |
| CD274 amplification |
Copy Number |
1 |
1 |
| CD30 + |
Protein expression |
5 |
6 |
| CD33 + |
Protein expression |
2 |
3 |
| CDK12 oncogenic variants |
Somatic Variant |
3 |
3 |
| CDK12 pathogenic variants |
Germline Variant |
3 |
3 |
| CHEK1 oncogenic variants |
Somatic Variant |
1 |
1 |
| CHEK1 pathogenic variants |
Germline Variant |
1 |
1 |
| CHEK2 oncogenic variants |
Somatic Variant |
2 |
2 |
| CHEK2 pathogenic variants |
Germline Variant |
2 |
2 |
| CLDN18.2 >= 75% |
Protein expression |
3 |
4 |
| EGFR Exon 19 (Deletion) |
Somatic Variant |
12 |
16 |
| EGFR Exon 20 (Insertion) |
Somatic Variant |
3 |
5 |
| EGFR oncogenic variants |
Somatic Variant |
6 |
7 |
| EGFR p.L858R |
Somatic Variant |
12 |
16 |
| EGFR p.T790M |
Somatic Variant |
1 |
2 |
| EGFR positive |
Protein expression |
6 |
6 |
| EGFR somatic variants |
Somatic Variant |
3 |
4 |
| ER negative |
Protein expression |
7 |
10 |
| ER positive |
Protein expression |
72 |
113 |
| ERBB2 amplification |
Copy Number |
18 |
23 |
| ERBB2 oncogenic variants |
Somatic Variant |
1 |
2 |
| ESR1 oncogenic variants |
Somatic Variant |
1 |
2 |
| EZH2 p.A692V |
Somatic Variant |
1 |
1 |
| EZH2 p.A862G |
Somatic Variant |
1 |
1 |
| EZH2 p.Y646C |
Somatic Variant |
1 |
1 |
| EZH2 p.Y646F |
Somatic Variant |
1 |
1 |
| EZH2 p.Y646H |
Somatic Variant |
1 |
1 |
| EZH2 p.Y646N |
Somatic Variant |
1 |
1 |
| EZH2 p.Y646S |
Somatic Variant |
1 |
1 |
| FANCA oncogenic variants |
Somatic Variant |
1 |
1 |
| FANCA pathogenic variants |
Germline Variant |
1 |
1 |
| FANCL oncogenic variants |
Somatic Variant |
1 |
1 |
| FANCL pathogenic variants |
Germline Variant |
1 |
1 |
| FGFR1 rearrangements |
Rearrangement |
1 |
1 |
| FGFR2 rearrangements |
Rearrangement |
3 |
3 |
| FGFR2::BICC1 |
Rearrangement |
1 |
1 |
| FGFR2::CASP7 |
Rearrangement |
1 |
1 |
| FGFR2::v |
Rearrangement |
4 |
5 |
| FGFR3 p.G370C |
Somatic Variant |
1 |
2 |
| FGFR3 p.R248C |
Somatic Variant |
1 |
2 |
| FGFR3 p.S249C |
Somatic Variant |
1 |
2 |
| FGFR3 p.Y373C |
Somatic Variant |
1 |
2 |
| FGFR3::BAIAP2L1 |
Rearrangement |
1 |
1 |
| FGFR3::TACC3 |
Rearrangement |
1 |
2 |
| FIP1L1::PDGFRA |
Rearrangement |
2 |
3 |
| FLT3 p.D835A |
Somatic Variant |
2 |
2 |
| FLT3 p.D835E |
Somatic Variant |
2 |
2 |
| FLT3 p.D835H |
Somatic Variant |
2 |
2 |
| FLT3 p.D835N |
Somatic Variant |
2 |
2 |
| FLT3 p.D835S |
Somatic Variant |
2 |
2 |
| FLT3 p.D835V |
Somatic Variant |
2 |
2 |
| FLT3 p.D835Y |
Somatic Variant |
3 |
3 |
| FLT3 p.I836del |
Somatic Variant |
1 |
1 |
| FLT3-ITD |
Somatic Variant |
3 |
4 |
| FOLR1 positive |
Protein expression |
3 |
3 |
| HER2-low |
Protein expression |
1 |
2 |
| HER2-negative |
Protein expression |
114 |
181 |
| HER2-positive |
Protein expression |
45 |
91 |
| HRD |
Homologous Recombination |
3 |
6 |
| IDH1 p.R132C |
Somatic Variant |
7 |
10 |
| IDH1 p.R132G |
Somatic Variant |
7 |
10 |
| IDH1 p.R132H |
Somatic Variant |
7 |
10 |
| IDH1 p.R132L |
Somatic Variant |
7 |
10 |
| IDH1 p.R132S |
Somatic Variant |
7 |
10 |
| IDH2 p.R140G |
Somatic Variant |
1 |
1 |
| IDH2 p.R140L |
Somatic Variant |
1 |
1 |
| IDH2 p.R140Q |
Somatic Variant |
1 |
1 |
| IDH2 p.R140W |
Somatic Variant |
1 |
1 |
| IDH2 p.R172G |
Somatic Variant |
3 |
3 |
| IDH2 p.R172K |
Somatic Variant |
3 |
3 |
| IDH2 p.R172M |
Somatic Variant |
3 |
3 |
| IDH2 p.R172S |
Somatic Variant |
3 |
3 |
| IDH2 p.R172W |
Somatic Variant |
3 |
3 |
| KIT p.D816V |
Somatic Variant |
1 |
1 |
| KRAS p.G12C |
Somatic Variant |
4 |
6 |
| KRAS p.G12V |
Somatic Variant |
1 |
1 |
| MET Exon 14 (Deletion) |
Somatic Variant |
2 |
4 |
| MET Exon 14 (Splice Site) |
Somatic Variant |
2 |
4 |
| MLH1 oncogenic variants |
Somatic Variant |
1 |
1 |
| MLH1 pathogenic variants |
Germline Variant |
1 |
1 |
| MRE11 oncogenic variants |
Somatic Variant |
1 |
1 |
| MRE11 pathogenic variants |
Germline Variant |
1 |
1 |
| MSI-H |
Microsatellite Stability |
10 |
16 |
| MSI-L |
Microsatellite Stability |
1 |
1 |
| NBN oncogenic variants |
Somatic Variant |
1 |
1 |
| NBN pathogenic variants |
Germline Variant |
1 |
1 |
| PALB2 oncogenic variants |
Somatic Variant |
2 |
2 |
| PALB2 pathogenic variants |
Germline Variant |
2 |
2 |
| PD-L1 (CPS) >= 1 |
Protein expression |
18 |
22 |
| PD-L1 (CPS) >= 10 |
Protein expression |
8 |
10 |
| PD-L1 (CPS) >= 5 |
Protein expression |
6 |
6 |
| PD-L1 < 1% |
Protein expression |
1 |
1 |
| PD-L1 >= 1% |
Protein expression |
14 |
16 |
| PD-L1 >= 10% TIIC |
Protein expression |
2 |
2 |
| PD-L1 >= 5% |
Protein expression |
1 |
1 |
| PD-L1 >= 50% |
Protein expression |
8 |
9 |
| PDGFRA p.D842V |
Somatic Variant |
1 |
2 |
| PDGFRA rearrangements |
Rearrangement |
2 |
3 |
| PDGFRB rearrangements |
Rearrangement |
2 |
3 |
| PIK3CA amplification |
Copy Number |
1 |
1 |
| PIK3CA somatic variants |
Somatic Variant |
9 |
9 |
| PIK3CA somatic variants |
Somatic Variant |
4 |
4 |
| PML::RARA |
Rearrangement |
1 |
3 |
| PR negative |
Protein expression |
9 |
12 |
| PR positive |
Protein expression |
67 |
100 |
| PTEN deletion |
Copy Number |
3 |
4 |
| PTEN frameshift variants |
Somatic Variant |
3 |
4 |
| PTEN nonsense variants |
Somatic Variant |
3 |
4 |
| PTEN splice site variants |
Somatic Variant |
3 |
4 |
| RAD51B oncogenic variants |
Somatic Variant |
1 |
1 |
| RAD51B pathogenic variants |
Germline Variant |
1 |
1 |
| RAD51C oncogenic variants |
Somatic Variant |
2 |
2 |
| RAD51C pathogenic variants |
Germline Variant |
2 |
2 |
| RAD51D oncogenic variants |
Somatic Variant |
1 |
1 |
| RAD51D pathogenic variants |
Germline Variant |
1 |
1 |
| RAD54L oncogenic variants |
Somatic Variant |
1 |
1 |
| RAD54L pathogenic variants |
Germline Variant |
1 |
1 |
| RET oncogenic variants |
Somatic Variant |
1 |
1 |
| RET p.M918T |
Somatic Variant |
1 |
1 |
| TMB-H (>= 10 mutations / Mb) |
Tumor mutational burden |
1 |
1 |
| TP53 deletion |
Copy Number |
2 |
2 |
| TP53 somatic variants |
Somatic Variant |
2 |
2 |
| TSC1 oncogenic variants |
Somatic Variant |
2 |
2 |
| TSC2 oncogenic variants |
Somatic Variant |
2 |
2 |
| Wild type ALK |
Wild type |
44 |
60 |
| Wild type EGFR |
Wild type |
44 |
60 |
| Wild type HRAS |
Wild type |
5 |
5 |
| Wild type KRAS |
Wild type |
11 |
12 |
| Wild type NRAS |
Wild type |
6 |
7 |
| Wild type ROS1 |
Wild type |
3 |
3 |
| Wild type TP53 |
Wild type |
1 |
1 |
| c-Met >= 50% |
Protein expression |
1 |
1 |
| dMMR |
Mismatch Repair |
13 |
20 |
| pMMR |
Mismatch Repair |
3 |
3 |
| t(15;17) |
Rearrangement |
1 |
2 |
| t(KMT2A;v) |
Rearrangement |
4 |
4 |
| v::ALK |
Rearrangement |
10 |
25 |
| v::BRAF |
Rearrangement |
1 |
1 |
| v::NRG1 |
Rearrangement |
2 |
2 |
| v::NTRK1 |
Rearrangement |
3 |
5 |
| v::NTRK2 |
Rearrangement |
3 |
5 |
| v::NTRK3 |
Rearrangement |
3 |
5 |
| v::RET |
Rearrangement |
7 |
10 |
| v::ROS1 |
Rearrangement |
4 |
6 |