EGFR Exon 20 (Insertion)
About
Gene context: EGFR
Biomarker Type: Somatic Variant
Present: True
Chromosome: 7
Variant Annotation: Insertion
Exon: 20
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.
| Organization(s) | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| EMA (1) FDA (1) | EGFR Exon 20 (Insertion) | Non-Small Cell Lung Cancer | Amivantamab, Carboplatin, Pemetrexed | |
| EMA (1) FDA (1) | EGFR Exon 20 (Insertion) | Non-Small Cell Lung Cancer | Amivantamab | |
| FDA (1) | EGFR Exon 20 (Insertion) | Non-Small Cell Lung Cancer | Mobocertinib | |
| FDA (1) | EGFR Exon 20 (Insertion) | Invasive Breast Carcinoma | Datopotamab deruxtecan | |
| FDA (1) | EGFR Exon 20 (Insertion) | Non-Small Cell Lung Cancer | Sunvozertinib |