EGFR oncogenic variants
About
Gene context: EGFR
Biomarker Type: Somatic Variant
Present: True
Chromosome: 7
Requires Oncogenic: True
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.
| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | EGFR oncogenic variants | Non-Small Cell Lung Cancer | Erlotinib, Ramucirumab | |
| Sensitivity (+) | EGFR oncogenic variants | Non-Small Cell Lung Cancer | Gefitinib | |
| Sensitivity (+) | EGFR oncogenic variants | Non-Small Cell Lung Cancer | Afatinib | |
| Sensitivity (+) | EGFR oncogenic variants | Non-Small Cell Lung Cancer | Osimertinib | |
| Sensitivity (+) | EGFR oncogenic variants | Non-Small Cell Lung Cancer | Erlotinib | |
| Sensitivity (+) | EGFR oncogenic variants | Non-Small Cell Lung Cancer | Erlotinib | |
| Sensitivity (+) | EGFR oncogenic variants | Non-Small Cell Lung Cancer | Dacomitinib |