Melanoma

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Mappings

OncoTree: Melanoma (oncotree:MEL)

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Therapeutic response

Precision oncology relationships for therapeutic response involving this cancer type.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) BRAF p.V600E Melanoma Binimetinib, Encorafenib
Sensitivity (+) BRAF p.V600K Melanoma Binimetinib, Encorafenib
Sensitivity (+) BRAF p.V600E Melanoma Cobimetinib, Vemurafenib
Sensitivity (+) BRAF p.V600K Melanoma Cobimetinib, Vemurafenib
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600E Melanoma Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Trametinib
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600E Melanoma Binimetinib, Encorafenib
Sensitivity (+) BRAF p.V600K Melanoma Binimetinib, Encorafenib
Sensitivity (+) PD-L1 < 1% Melanoma Nivolumab, Relatlimab
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Dabrafenib
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600E Melanoma Vemurafenib
Sensitivity (+) BRAF p.V600K Melanoma Vemurafenib
Sensitivity (+) BRAF p.V600E Melanoma Atezolizumab, Cobimetinib, Vemurafenib
Sensitivity (+) BRAF p.V600K Melanoma Atezolizumab, Cobimetinib, Vemurafenib
Sensitivity (+) BRAF p.V600E Melanoma Binimetinib, Encorafenib
Sensitivity (+) BRAF p.V600K Melanoma Binimetinib, Encorafenib
Sensitivity (+) BRAF p.V600E Melanoma Cobimetinib, Vemurafenib
Sensitivity (+) BRAF p.V600K Melanoma Cobimetinib, Vemurafenib
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600E Melanoma Binimetinib, Encorafenib
Sensitivity (+) BRAF p.V600K Melanoma Binimetinib, Encorafenib
Sensitivity (+) BRAF p.V600E Melanoma Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Trametinib
Sensitivity (+) BRAF p.V600E Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600K Melanoma Dabrafenib, Trametinib
Sensitivity (+) BRAF p.V600E Melanoma Vemurafenib