MLH1
About
Location: 3p22.2
Mappings
Biomarkers
MLH1 is involved in the following curated biomarkers.
| Name | Biomarker type | Propositions | Statements |
|---|---|---|---|
| MLH1 oncogenic variants | Somatic Variant | 1 | 1 |
| MLH1 pathogenic variants | Germline Variant | 1 | 1 |
Therapeutic response
Precision oncology relationships for therapeutic response involving this gene.
| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | MLH1 oncogenic variants | Prostate Adenocarcinoma | Enzalutamide, Talazoparib | |
| Sensitivity (+) | MLH1 pathogenic variants | Prostate Adenocarcinoma | Enzalutamide, Talazoparib |